The first stage of my GEMINI diagnostic matrix is the identification of inherited and genetic risk. This will show any weak spots that provide opportunities for infection, inflammation and injury.
The family history is the critical key to understanding inheritance, but an increasing number of genetic tests are proving useful for identifying methylation defects, predisposition to infection, gluten reactivity and autoimmunity and even adverse drug reactions and dosage requirements.
Irrespective of the genetics, epigenetic expression under the influence of diet, stress, and even the microbiome of the gut is the hot new area of research. A body of evidence for transgenerational inheritance of acquired epigenetic changes is growing.
As if that weren't enough, we are now seeing the re-emergence of human endogenous retroviruses (HERV), ancient viruses copied into our DNA and thought to be fossils of past infections. Research in the areas of autoimmunity and even chronic fatigue syndrome seem to be showing that these long "dead" DNA viral segments are resurrecting and inducing abnormal immune responses as we fight our old enemies.
Knowing enough about genetics and epigenetic expression to keep away from some common trapdoors and reduce some of the risks is the first step of GEMINI.